The biological phenomena are governed by complex network systems including many species of molecules, cells or organs. For the aim of understanding the functions of complex systems, we adopt mathematical and computational methods.
By theoretical approaches we decipher huge amounts of experimental information, and give integrative understanding for the biological systems.
Our final goal is to open a new bioscience which will progress by the repeats of the theoretical predictions and the experimental verifications.
RESEARCH
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Complete control of a gene regulatory network of ascidian embryo by a few factors identified by a mathematical theory.
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Determining responses of chemical reaction systems from structure of networks
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Structure and dynamics of regulatory networks
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Physics of organelle morphogenesis
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NEWS
- publication
Prof. Mochizuki’s interview was published in Kyoto Shimbun.
- publication
Mochizuki A.* (2022) A structural approach to understanding enzymatic regulation of chemical reaction networks. Biochem. J. 479(11), 1265–1283.
- publication
Kinoshita A, Naito M., Wang Z., Inoue Y., Mochizuki A. and Tsukaya H. (2022) Position of meristems and the angles of the cell division plane regulate the uniqueness of lateral organ shape. Development 149(23), dev199733.
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Okada T., Miyagi H., Sako Y., Hiroshima M.*, and Mochizuki A.* (2022) Origin of diverse phosphorylation patterns in the ERBB system Biophysical Journal 121, 470–480.
- publication
Akaki K., Ogata K., Yamauchi Y., Iwai No., Tse K. M., Hia F., Mochizuki A., Ishihama Y., Mino T., Takeuchi O. (2021) IRAK1-dependentRegnase-1-14-3-3 complex formation controls Regnase-1-mediated mRNA decay. eLife 10, e71966. doi: 10.7554/eLife.71966
- publication
Prof. Mochizuki’s interview was published in Kyoto Shimbun.
- publication
Mochizuki A.* (2022) A structural approach to understanding enzymatic regulation of chemical reaction networks. Biochem. J. 479(11), 1265–1283.
- publication
Kinoshita A, Naito M., Wang Z., Inoue Y., Mochizuki A. and Tsukaya H. (2022) Position of meristems and the angles of the cell division plane regulate the uniqueness of lateral organ shape. Development 149(23), dev199733.
- publication
Okada T., Miyagi H., Sako Y., Hiroshima M.*, and Mochizuki A.* (2022) Origin of diverse phosphorylation patterns in the ERBB system Biophysical Journal 121, 470–480.
- publication
Akaki K., Ogata K., Yamauchi Y., Iwai No., Tse K. M., Hia F., Mochizuki A., Ishihama Y., Mino T., Takeuchi O. (2021) IRAK1-dependentRegnase-1-14-3-3 complex formation controls Regnase-1-mediated mRNA decay. eLife 10, e71966. doi: 10.7554/eLife.71966